Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function

Although the C-terminal cytoplasmic tail of the tight junction protein occludin is heavily phosphorylated, the functional impact of most individual sites is undefined. Here, we show that inhibition of CK2-mediated occludin S408 phosphorylation elevates transepithelial resistance by reducing paracell...

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Main Authors: Raleigh, David R., Boe, Devin M., Yu, Dan, Weber, Christopher R., Marchiando, Amanda M., Bradford, Emily M., Wang, Yingmin, Wu, Licheng, Schneeberger, Eveline E., Shen, Le, Turner, Jerrold R.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2011
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087007/
https://ncbi.nlm.nih.gov/pubmed/21536752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010065
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