Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

Epithelial paracellular barrier function, determined primarily by tight junction permeability, is frequently disrupted in disease. In the intestine, barrier loss can be mediated by tumor necrosis factor (α) (TNF) signaling and epithelial myosin light chain kinase (MLCK) activation. However, TNF indu...

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Main Authors: Marchiando, Amanda M., Shen, Le, Graham, W. Vallen, Weber, Christopher R., Schwarz, Brad T., Austin, Jotham R., Raleigh, David R., Guan, Yanfang, Watson, Alastair J.M., Montrose, Marshall H., Turner, Jerrold R.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2010
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854371/
https://ncbi.nlm.nih.gov/pubmed/20351069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200902153
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