Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

Epithelial paracellular barrier function, determined primarily by tight junction permeability, is frequently disrupted in disease. In the intestine, barrier loss can be mediated by tumor necrosis factor (α) (TNF) signaling and epithelial myosin light chain kinase (MLCK) activation. However, TNF indu...

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Detalhes bibliográficos
Main Authors: Marchiando, Amanda M., Shen, Le, Graham, W. Vallen, Weber, Christopher R., Schwarz, Brad T., Austin, Jotham R., Raleigh, David R., Guan, Yanfang, Watson, Alastair J.M., Montrose, Marshall H., Turner, Jerrold R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854371/
https://ncbi.nlm.nih.gov/pubmed/20351069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200902153
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