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Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo
Epithelial paracellular barrier function, determined primarily by tight junction permeability, is frequently disrupted in disease. In the intestine, barrier loss can be mediated by tumor necrosis factor (α) (TNF) signaling and epithelial myosin light chain kinase (MLCK) activation. However, TNF indu...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Rockefeller University Press
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854371/ https://ncbi.nlm.nih.gov/pubmed/20351069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200902153 |
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