Loading...

The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding

BACKGROUND & AIMS: Tumor necrosis factor (TNF) increases intestinal epithelial cell shedding and apoptosis, potentially challenging the barrier between the gastrointestinal lumen and internal tissues. We investigated the mechanism of tight junction remodeling and barrier maintenance, as well as...

Full description

Saved in:
Bibliographic Details
Main Authors: Marchiando, Amanda M., Shen, Le, Graham, W. Vallen, Edelblum, Karen L., Duckworth, Carrie A., Guan, Yanfang, Montrose, Marshall H., Turner, Jerrold R., Watson, Alastair J.M.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066304/
https://ncbi.nlm.nih.gov/pubmed/21237166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.01.004
Tags: Add Tag
No Tags, Be the first to tag this record!