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The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding
BACKGROUND & AIMS: Tumor necrosis factor (TNF) increases intestinal epithelial cell shedding and apoptosis, potentially challenging the barrier between the gastrointestinal lumen and internal tissues. We investigated the mechanism of tight junction remodeling and barrier maintenance, as well as...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066304/ https://ncbi.nlm.nih.gov/pubmed/21237166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.01.004 |
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