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Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux

In vitro and in vivo studies implicate occludin in the regulation of paracellular macromolecular flux at steady state and in response to tumor necrosis factor (TNF). To define the roles of occludin in these processes, we established intestinal epithelia with stable occludin knockdown. Knockdown mono...

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Autors principals: Buschmann, Mary M., Shen, Le, Rajapakse, Harsha, Raleigh, David R., Wang, Yitang, Wang, Yingmin, Lingaraju, Amulya, Zha, Juanmin, Abbott, Elliot, McAuley, Erin M., Breskin, Lydia A., Wu, Licheng, Anderson, Kenneth, Turner, Jerrold R., Weber, Christopher R.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784380/
https://ncbi.nlm.nih.gov/pubmed/23924897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-09-0688
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