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Meprin A impairs epithelial barrier function, enhances monocyte migration, and cleaves the tight junction protein occludin
Meprin metalloproteases are highly expressed at the luminal interface of the intestine and kidney and in certain leukocytes. Meprins cleave a variety of substrates in vitro, including extracellular matrix proteins, adherens junction proteins, and cytokines, and have been implicated in a number of in...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761208/ https://ncbi.nlm.nih.gov/pubmed/23804454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00179.2012 |
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