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Directed Evolution of DNA Polymerases for Next Generation Sequencing
[Image: see text] We present the application of an activity-based phage display method to identify DNA polymerases tailored for next generation sequencing applications. Using this approach, we identify a mutant of Taq DNA polymerase that incorporates the fluorophore-labeled dA, dT, dC, and dG substr...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043640/ https://ncbi.nlm.nih.gov/pubmed/20629059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201001607 |
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