Chelation of intracellular calcium blocks insulin action in the adipocyte.
The hypothesis that intracellular Ca2+ is an essential component of the intracellular mechanism of insulin action in the adipocyte was evaluated. Cells were loaded with the Ca2+ chelator quin-2, by preincubating them with quin-2 AM, the tetrakis(acetoxymethyl) ester of quin-2. Quin-2 loading inhibit...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1987
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304354/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3103120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.4.1025 |
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