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Chelation of intracellular calcium blocks insulin action in the adipocyte.

The hypothesis that intracellular Ca2+ is an essential component of the intracellular mechanism of insulin action in the adipocyte was evaluated. Cells were loaded with the Ca2+ chelator quin-2, by preincubating them with quin-2 AM, the tetrakis(acetoxymethyl) ester of quin-2. Quin-2 loading inhibit...

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Detalles Bibliográficos
Main Authors: Pershadsingh, H A, Shade, D L, Delfert, D M, McDonald, J M
Formato: Artigo
Idioma:Inglês
Publicado: 1987
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC304354/
https://ncbi.nlm.nih.gov/pubmed/3103120
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