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Partial disruption of naturally occurring groups of insulin receptors on adipocyte plasma membranes by dithiothreitol and N-ethylmaleimide: the role of disulfide bonds.

In this ultrastructural study, monomeric ferritin-insulin was used to further elucidate the role of disulfide bonds in maintaining the natural groups of insulin receptors on adipocyte plasma membranes. Dithiothreitol (1 mM) caused partial disruption of the occupied receptor groups with an increase i...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Jarett, L, Smith, R M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393520/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6341987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.4.1023
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