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Partial disruption of naturally occurring groups of insulin receptors on adipocyte plasma membranes by dithiothreitol and N-ethylmaleimide: the role of disulfide bonds.

In this ultrastructural study, monomeric ferritin-insulin was used to further elucidate the role of disulfide bonds in maintaining the natural groups of insulin receptors on adipocyte plasma membranes. Dithiothreitol (1 mM) caused partial disruption of the occupied receptor groups with an increase i...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Jarett, L, Smith, R M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393520/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6341987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.4.1023
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