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Partial disruption of naturally occurring groups of insulin receptors on adipocyte plasma membranes by dithiothreitol and N-ethylmaleimide: the role of disulfide bonds.

In this ultrastructural study, monomeric ferritin-insulin was used to further elucidate the role of disulfide bonds in maintaining the natural groups of insulin receptors on adipocyte plasma membranes. Dithiothreitol (1 mM) caused partial disruption of the occupied receptor groups with an increase i...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Jarett, L, Smith, R M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1983
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393520/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6341987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.4.1023
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