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Orthogonal use of a human tRNA synthetase active site to achieve multi-functionality
Protein multi-functionality is an emerging explanation for the complexity of higher organisms. In this regard, while aminoacyl tRNA synthetases catalyze amino acid activation for protein synthesis, some also act in pathways for inflammation, angiogenesis, and apoptosis. How multiple functions evolve...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042952/ https://ncbi.nlm.nih.gov/pubmed/20010843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1706 |
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