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Orthogonal use of a human tRNA synthetase active site to achieve multi-functionality
Protein multi-functionality is an emerging explanation for the complexity of higher organisms. In this regard, while aminoacyl tRNA synthetases catalyze amino acid activation for protein synthesis, some also act in pathways for inflammation, angiogenesis, and apoptosis. How multiple functions evolve...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042952/ https://ncbi.nlm.nih.gov/pubmed/20010843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1706 |
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