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An update on targeted gene repair in mammalian cells: methods and mechanisms
Transfer of full-length genes including regulatory elements has been the preferred gene therapy strategy for clinical applications. However, with significant drawbacks emerging, targeted gene alteration (TGA) has recently become a promising alternative to this method. By means of TGA, endogenous DNA...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042377/ https://ncbi.nlm.nih.gov/pubmed/21284895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-10 |
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