Pharmacology of structural changes at the GABA(A) receptor transmitter binding site

BACKGROUND AND PURPOSE: The binding of transmitter to specialized binding pockets leads to rearrangements in the structure of the receptor eventually resulting in channel opening. We used voltage-clamp fluorometry to investigate the pharmacological basis and biophysical processes that underlie struc...

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Autori principali: Akk, Gustav, Li, Ping, Bracamontes, John, Wang, Mengya, Steinbach, Joe Henry
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2011
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042195/
https://ncbi.nlm.nih.gov/pubmed/20958292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01083.x
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