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Accumulation of lysosulfatide in the brain of arylsulfatase A-deficient mice

Lysosomal storage diseases are a group of disorders where accumulation of catabolites is manifested in the lysosomes of different cell types. In metachromatic leukodystrophy (Arylsulfatase A [EC.3.1.6.8] deficiency) storage of the glycosphingolipid sulfatide in the brain leads to demyelination, resu...

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Autores principales: Blomqvist, Maria, Gieselmann, Volkmar, Månsson, Jan-Eric
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041674/
https://ncbi.nlm.nih.gov/pubmed/21299873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-10-28
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