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Transport of Arylsulfatase A across the Blood-Brain Barrier in Vitro

Enzyme replacement therapy is an option to treat lysosomal storage diseases caused by functional deficiencies of lysosomal hydrolases as intravenous injection of therapeutic enzymes can correct the catabolic defect within many organ systems. However, beneficial effects on central nervous system mani...

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Detalhes bibliográficos
Main Authors: Matthes, Frank, Wölte, Philipp, Böckenhoff, Annika, Hüwel, Sabine, Schulz, Mareike, Hyden, Pia, Fogh, Jens, Gieselmann, Volkmar, Galla, Hans-Joachim, Matzner, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093822/
https://ncbi.nlm.nih.gov/pubmed/21454621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.189381
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