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Arylsulfatase A deficiency causes seminolipid accumulation and a lysosomal storage disorder in Sertoli cells
Sulfogalactosylglycerolipid (SGG) is the major sulfoglycolipid of male germ cells. During spermatogenesis, apoptosis occurs in >50% of total germ cells. Sertoli cells phagocytose these apoptotic germ cells and degrade their components using lysosomal enzymes. Here we demonstrated that SGG was a p...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220287/ https://ncbi.nlm.nih.gov/pubmed/21965315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M019661 |
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