α-Synuclein Negatively Regulates Protein Kinase Cδ Expression to Suppress Apoptosis in Dopaminergic Neurons by Reducing p300 Histone Acetyltransferase Activity

We recently demonstrated that protein kinase Cδ (PKCδ), an important member of the novel PKC family, is a key oxidative stress-sensitive kinase that can be activated by caspase-3-dependent proteolytic cleavage to induce dopaminergic neuronal cell death. We now report a novel association between α-sy...

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Bibliographische Detailangaben
Hauptverfasser: Jin, Huajun, Kanthasamy, Arthi, Ghosh, Anamitra, Yang, Yongjie, Anantharam, Vellareddy, Kanthasamy, Anumantha G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2011
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041642/
https://ncbi.nlm.nih.gov/pubmed/21307242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5634-10.2011
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