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Vascular actions of calcimimetics: role of Ca(2+)-sensing receptors versus Ca(2+) influx through L-type Ca(2+) channels
BACKGROUND AND PURPOSE: The calcimimetic, (R)-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-(1-napthyl)ethylamine hydrochloride (cinacalcet), which activates Ca(2+)-sensing receptors (CaR) in parathyroid glands, is used to treat hyperparathyroidism. Interestingly, CaR in perivascular nerves or endotheli...
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Formato: | Artigo |
Lenguaje: | Inglês |
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Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041262/ https://ncbi.nlm.nih.gov/pubmed/20958288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01079.x |
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