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Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activate pathological hypertrophy signaling

Common cardiovascular diseases such as hypertension and myocardial infarction require that myocytes develop greater than normal force to maintain cardiac pump function. This requires increases in [Ca(2+)]. These diseases induce cardiac hypertrophy and increases in [Ca(2+)] are known to be an essenti...

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Detalhes bibliográficos
Main Authors: Gao, Hui, Wang, Fang, Wang, Wei, Makarewich, Catherine A., Zhang, Hongyu, Kubo, Hajime, Berretta, Remus M., Barr, Larry A., Molkentin, Jeffrey D., Houser, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472041/
https://ncbi.nlm.nih.gov/pubmed/22921230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.08.005
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