Evidence for an Unanticipated Relationship Between Undifferentiated Pleomorphic Sarcoma and Embryonal Rhabdomyosarcoma

Embryonal rhabdomyosarcoma (eRMS) shows the most myodifferentiation amongst sarcomas, yet the precise cell of origin remains undefined. Using Ptch1, p53 and/or Rb1 conditional mouse models and controlling prenatal or postnatal myogenic cell of origin, we demonstrate that eRMS and undifferentiated pl...

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Détails bibliographiques
Auteurs principaux: Rubin, Brian P., Nishijo, Koichi, Chen, Hung-I Harry, Yi, Xiaolan, Schuetze, David P., Pal, Ranadip, Prajapati, Suresh I., Abraham, Jinu, Arenkiel, Benjamin R., Chen, Qing-Rong, Davis, Sean, McCleish, Amanda T., Capecchi, Mario R., Michalek, Joel E., Zarzabal, Lee Ann, Khan, Javed, Yu, Zhongxin, Parham, David M., Barr, Frederic G., Meltzer, Paul S., Chen, Yidong, Keller, Charles
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040414/
https://ncbi.nlm.nih.gov/pubmed/21316601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.12.023
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