Lineage of origin in rhabdomyosarcoma informs pharmacological response

Lineage or cell of origin of cancers is often unknown and thus is not a consideration in therapeutic approaches. Alveolar rhabdomyosarcoma (aRMS) is an aggressive childhood cancer for which the cell of origin remains debated. We used conditional genetic mouse models of aRMS to activate the pathognom...

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Detalhes bibliográficos
Main Authors: Abraham, Jinu, Nuñez-Álvarez, Yaiza, Hettmer, Simone, Carrió, Elvira, Chen, Hung-I Harry, Nishijo, Koichi, Huang, Elaine T., Prajapati, Suresh I., Walker, Robert L., Davis, Sean, Rebeles, Jennifer, Wiebush, Hunter, McCleish, Amanda T., Hampton, Sheila T., Bjornson, Christopher R.R., Brack, Andrew S., Wagers, Amy J., Rando, Thomas A., Capecchi, Mario R., Marini, Frank C., Ehler, Benjamin R., Zarzabal, Lee Ann, Goros, Martin W., Michalek, Joel E., Meltzer, Paul S., Langenau, David M., LeGallo, Robin D., Mansoor, Atiya, Chen, Yidong, Suelves, Mònica, Rubin, Brian P., Keller, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102765/
https://ncbi.nlm.nih.gov/pubmed/25030697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.238733.114
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