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Alterations of the retinoblastoma gene in metastatic breast cancer

Germline mutations affecting the retinoblastoma gene (RB1) predispose to inherited retinoblastomas but also other malignancies, including breast cancer. While somatic RB1 mutations have been detected in different malignancies, information about the potential role of RB1 mutations in breast cancer is...

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Hlavní autoři: Berge, Elisabet Ognedal, Knappskog, Stian, Lillehaug, Johan Richard, Lønning, Per Eystein
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040352/
https://ncbi.nlm.nih.gov/pubmed/21253829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-011-9375-y
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