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Alterations of the retinoblastoma gene in metastatic breast cancer

Germline mutations affecting the retinoblastoma gene (RB1) predispose to inherited retinoblastomas but also other malignancies, including breast cancer. While somatic RB1 mutations have been detected in different malignancies, information about the potential role of RB1 mutations in breast cancer is...

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Dettagli Bibliografici
Autori principali: Berge, Elisabet Ognedal, Knappskog, Stian, Lillehaug, Johan Richard, Lønning, Per Eystein
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040352/
https://ncbi.nlm.nih.gov/pubmed/21253829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-011-9375-y
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