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Alterations of the retinoblastoma gene in metastatic breast cancer

Germline mutations affecting the retinoblastoma gene (RB1) predispose to inherited retinoblastomas but also other malignancies, including breast cancer. While somatic RB1 mutations have been detected in different malignancies, information about the potential role of RB1 mutations in breast cancer is...

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Detalhes bibliográficos
Main Authors: Berge, Elisabet Ognedal, Knappskog, Stian, Lillehaug, Johan Richard, Lønning, Per Eystein
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040352/
https://ncbi.nlm.nih.gov/pubmed/21253829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-011-9375-y
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