Malformation of certain brain blood vessels caused by TCDD activation of Ahr2/Arnt1 signaling in developing zebrafish

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) causes various signs of toxicity in early life stages of vertebrates through activation of the aryl hydrocarbon receptor (AHR). The AHR also plays important roles in normal development in mice, and AHR(-/-) mice show abnormal development of vascular structu...

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Hoofdauteurs: Teraoka, Hiroki, Ogawa, Akira, Kubota, Akira, Stegeman, John J., Peterson, Richard E., Hiraga, Takeo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040289/
https://ncbi.nlm.nih.gov/pubmed/20554057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aquatox.2010.05.003
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