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Ahr2-dependance of PCB126 effects on the swimbladder in relation to expression of CYP1 and cox-2 genes in developing zebrafish

The teleost swimbladder is assumed a homolog of the tetrapod lung. Both swimbladder and lung are developmental targets of persistent aryl hydrocarbon receptor (AHR) agonists; in zebrafish (Danio rerio) the swimbladder fails to inflate with exposure to 3,3’,4,4’,5-pentachlorobiphenyl (PCB126). The me...

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Detalhes bibliográficos
Main Authors: Jönsson, Maria E., Kubota, Akira, Timme-Laragy, Alicia, Woodin, Bruce, Stegeman, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529150/
https://ncbi.nlm.nih.gov/pubmed/23036320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.09.023
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