The emerging contaminant 3,3’-dichlorobiphenyl (PCB-11) impedes Ahr activation and Cyp1a activity to modify embryotoxicity of Ahr ligands in the zebrafish embryo model (Danio rerio)

3,3’-dichlorobiphenyl (PCB-11) is an emerging PCB congener widely detected in environmental samples and human serum, but its toxicity potential is poorly understood. We assessed the effects of three concentrations of PCB-11 on embryotoxicity and Aryl hydrocarbon receptor (Ahr) pathway interactions i...

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Udgivet i:Environ Pollut
Main Authors: Roy, Monika A., Sant, Karilyn E., Venezia, Olivia L., Shipman, Alix B., McCormick, Stephen D., Saktrakulkla, Panithi, Hornbuckle, Keri C., Timme-Laragy, Alicia R.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027435/
https://ncbi.nlm.nih.gov/pubmed/31421573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envpol.2019.113027
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