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Involvement of COX2-Thromboxane Pathway in TCDD-Induced Precardiac Edema in Developing Zebrafish

The cardiovascular system is one of the most characteristic and important targets for developmental toxicity by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in fish larvae. However, knowledge of the mechanism of TCDD-induced edema after heterodimerization of aryl hydrocarbon receptor type 2 (AHR2) and...

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Bibliographic Details
Published in:Aquat Toxicol
Main Authors: Teraoka, Hiroki, Okuno, Yuki, Nijoukubo, Daisuke, Yamakoshi, Ayumi, Peterson, Richard E., Stegeman, John J., Kitazawa, Takio, Hiraga, Takeo, Kubota, Akira
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326229/
https://ncbi.nlm.nih.gov/pubmed/24858302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aquatox.2014.04.025
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