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Circular Single-Stranded Synthetic DNA Delivery Vectors for MicroRNA

Single-stranded (ss) circular oligodeoxynucleotides were previously found to undergo rolling circle transcription (RCT) by phage and bacterial RNA polymerases (RNAPs) into tandemly repetitive RNA multimers. Here, we redesign them to encode minimal primary miRNA mimics, with the long term aim of intr...

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Detaylı Bibliyografya
Asıl Yazarlar: Seidl, Christine I., Ryan, Kevin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040211/
https://ncbi.nlm.nih.gov/pubmed/21359172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016925
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