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Circular Single-Stranded Synthetic DNA Delivery Vectors for MicroRNA
Single-stranded (ss) circular oligodeoxynucleotides were previously found to undergo rolling circle transcription (RCT) by phage and bacterial RNA polymerases (RNAPs) into tandemly repetitive RNA multimers. Here, we redesign them to encode minimal primary miRNA mimics, with the long term aim of intr...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040211/ https://ncbi.nlm.nih.gov/pubmed/21359172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016925 |
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