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α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways

BACKGROUND: α-Tocopherol ether-linked acetic acid (α-TEA) is a promising agent for cancer prevention/therapy based on its antitumour actions in a variety of cancers. METHODS: Human breast cancer cells, MCF-7 and HCC-1954, were used to study the effect of α-TEA using Annexin V/PI staining, western bl...

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Detalhes bibliográficos
Main Authors: Tiwary, R, Yu, W, Sanders, B G, Kline, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039802/
https://ncbi.nlm.nih.gov/pubmed/21119656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6606019
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