Triplex forming oligonucleotide targeted to 3′UTR downregulates the expression of the bcl-2 proto-oncogene in HeLa cells

The bcl-2 proto-oncogene is overexpressed in a variety of human cancers and plays an important role in programmed cell death. Recent reports implied that the 3′-untranslated region (3′UTR) functions effectively in the regulation of gene expression. Here, we attempt to assay the ability of triplex fo...

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Hlavní autoři: Shen, Changxian, Buck, Andreas, Mehrke, Gerhard, Polat, Bülent, Gross, Hans-Jügen, Bachem, Max, Reske, Sven
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC30398/
https://ncbi.nlm.nih.gov/pubmed/11160882
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