Triplex forming oligonucleotide targeted to 3′UTR downregulates the expression of the bcl-2 proto-oncogene in HeLa cells

The bcl-2 proto-oncogene is overexpressed in a variety of human cancers and plays an important role in programmed cell death. Recent reports implied that the 3′-untranslated region (3′UTR) functions effectively in the regulation of gene expression. Here, we attempt to assay the ability of triplex fo...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Shen, Changxian, Buck, Andreas, Mehrke, Gerhard, Polat, Bülent, Gross, Hans-Jügen, Bachem, Max, Reske, Sven
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160882/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.3.622
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