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Traf6 and A20 differentially regulate TLR4-induced autophagy by affecting the ubiquitination of Beclin 1
Toll-like receptor 4 (TLR4) signaling triggers autophagy, which has been linked to both adaptive and innate immunity. Engagement of TLR4 recruits to the receptor complex Beclin 1, a key component of a class III phosphatidylinositol 3-kinase complex (PI3KC3) that initiates autophagosome formation. Re...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039745/ https://ncbi.nlm.nih.gov/pubmed/20798608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.7.13288 |
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