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Cleaving Beclin 1 to suppress autophagy in chemotherapy-induced apoptosis

Autophagy is often found in apoptosis-defective cancer cells and contributes to chemotherapy resistance. However, it is far from clear how the coordination of apoptosis and autophagy determines sensitivity of cancer cells to chemotherapy. Our recent study showed that Beclin 1, a key regulator of aut...

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Autors principals: Li, Hua, Wang, Peng, Yu, Jian, Zhang, Lin
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210308/
https://ncbi.nlm.nih.gov/pubmed/21610315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.10.16490
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