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Cleaving Beclin 1 to suppress autophagy in chemotherapy-induced apoptosis
Autophagy is often found in apoptosis-defective cancer cells and contributes to chemotherapy resistance. However, it is far from clear how the coordination of apoptosis and autophagy determines sensitivity of cancer cells to chemotherapy. Our recent study showed that Beclin 1, a key regulator of aut...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Landes Bioscience
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210308/ https://ncbi.nlm.nih.gov/pubmed/21610315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.10.16490 |
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