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Insertion of the v-Ha-ras oncogene induces differentiation of calcitonin-producing human small cell lung cancer.

Human small cell lung cancers (SCLC) and cell lines derived therefrom are phenotypically heterogeneous concerning neuroendocrine differentiation. Unlike most SCLC tumors and cell lines that express poorly differentiated neuroendocrine phenotypes, the SCLC cell line DMS 53 exhibits mature endocrine d...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Mabry, M, Nakagawa, T, Baylin, S, Pettengill, O, Sorenson, G, Nelkin, B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303969/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2544624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114140
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