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v-rasH induces non-small cell phenotype, with associated growth factors and receptors, in a small cell lung cancer cell line.

Small cell lung cancer (SCLC) tumor progression can involve partial or complete conversion to a more treatment-resistant non-small cell (NSCLC) phenotype. In a cell culture model of this phenomenon, we have previously demonstrated that insertion of the viral Harvey ras gene (v-Ha-ras) into SCLC cell...

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Udgivet i:J Clin Invest
Principais autores: Falco, J P, Baylin, S B, Lupu, R, Borges, M, Nelkin, B D, Jasti, R K, Davidson, N E, Mabry, M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296635/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2161428/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114630
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