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RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas.

An activated ras oncogene induces a program of differentiation in the human medullary thyroid cancer cell line TT. This differentiation process is accompanied by a marked increase in the transcription of the human calcitonin (CT) gene. We have localized a unique Ras-responsive transcriptional elemen...

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Bibliographic Details
Main Authors: Thiagalingam, A, De Bustros, A, Borges, M, Jasti, R, Compton, D, Diamond, L, Mabry, M, Ball, D W, Baylin, S B, Nelkin, B D
Format: Artigo
Language:Inglês
Published: 1996
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC231532/
https://ncbi.nlm.nih.gov/pubmed/8816445
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