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Insertion of the v-Ha-ras oncogene induces differentiation of calcitonin-producing human small cell lung cancer.

Human small cell lung cancers (SCLC) and cell lines derived therefrom are phenotypically heterogeneous concerning neuroendocrine differentiation. Unlike most SCLC tumors and cell lines that express poorly differentiated neuroendocrine phenotypes, the SCLC cell line DMS 53 exhibits mature endocrine d...

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Vydáno v:J Clin Invest
Hlavní autoři: Mabry, M, Nakagawa, T, Baylin, S, Pettengill, O, Sorenson, G, Nelkin, B
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1989
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303969/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2544624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114140
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