Enhanced Mucosal Immune Responses to HIV Virus-Like Particles Containing a Membrane-Anchored Adjuvant

Previously, a modified HIV Env protein with a heterologous membrane anchor was found to be incorporated into HIV virus-like particles (VLPs) at 10-fold-higher levels than those of unmodified Env. To further improve the immunogenicity of such VLPs, membrane-anchored forms of bacterial flagellin (FliC...

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Detalhes bibliográficos
Main Authors: Vassilieva, Elena V., Wang, Bao-Zhong, Vzorov, Andrei N., Wang, Li, Wang, Ying-Chun, Bozja, Jadranka, Xu, Rui, Compans, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039440/
https://ncbi.nlm.nih.gov/pubmed/21325038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00328-10
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