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Crystal Structure of a Josephin-Ubiquitin Complex: EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATING ACTIVITY

The Josephin domain is a conserved cysteine protease domain found in four human deubiquitinating enzymes: ataxin-3, the ataxin-3-like protein (ATXN3L), Josephin-1, and Josephin-2. Josephin domains from these four proteins were purified and assayed for their ability to cleave ubiquitin substrates. Re...

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Hlavní autoři: Weeks, Stephen D., Grasty, Kimberly C., Hernandez-Cuebas, Lisa, Loll, Patrick J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039388/
https://ncbi.nlm.nih.gov/pubmed/21118805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177360
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