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Crystal Structure of a Josephin-Ubiquitin Complex: EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATING ACTIVITY

The Josephin domain is a conserved cysteine protease domain found in four human deubiquitinating enzymes: ataxin-3, the ataxin-3-like protein (ATXN3L), Josephin-1, and Josephin-2. Josephin domains from these four proteins were purified and assayed for their ability to cleave ubiquitin substrates. Re...

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書誌詳細
主要な著者: Weeks, Stephen D., Grasty, Kimberly C., Hernandez-Cuebas, Lisa, Loll, Patrick J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039388/
https://ncbi.nlm.nih.gov/pubmed/21118805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177360
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