Small Ubiquitin-related Modifier (SUMO)-1 Promotes Glycolysis in Hypoxia

Under conditions of hypoxia, most eukaryotic cells undergo a shift in metabolic strategy, which involves increased flux through the glycolytic pathway. Although this is critical for bioenergetic homeostasis, the underlying mechanisms have remained incompletely understood. Here, we report that the in...

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Hlavní autoři: Agbor, Terence A., Cheong, Alex, Comerford, Katrina M., Scholz, Carsten C., Bruning, Ulrike, Clarke, Ambrose, Cummins, Eoin P., Cagney, Gerard, Taylor, Cormac T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039330/
https://ncbi.nlm.nih.gov/pubmed/21123177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115931
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