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MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1α Activity during Prolonged Hypoxia

The hypoxia-inducible factor (HIF) is a key regulator of the transcriptional response to hypoxia. While the mechanism underpinning HIF activation is well understood, little is known about its resolution. Both the protein and the mRNA levels of HIF-1α (but not HIF-2α) were decreased in intestinal epi...

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Detalhes bibliográficos
Main Authors: Bruning, Ulrike, Cerone, Luca, Neufeld, Zoltan, Fitzpatrick, Susan F., Cheong, Alex, Scholz, Carsten C., Simpson, David A., Leonard, Martin O., Tambuwala, Murtaza M., Cummins, Eoin P., Taylor, Cormac T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187364/
https://ncbi.nlm.nih.gov/pubmed/21807897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01276-10
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