Small Ubiquitin-related Modifier (SUMO)-1 Promotes Glycolysis in Hypoxia

Under conditions of hypoxia, most eukaryotic cells undergo a shift in metabolic strategy, which involves increased flux through the glycolytic pathway. Although this is critical for bioenergetic homeostasis, the underlying mechanisms have remained incompletely understood. Here, we report that the in...

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Detalhes bibliográficos
Main Authors: Agbor, Terence A., Cheong, Alex, Comerford, Katrina M., Scholz, Carsten C., Bruning, Ulrike, Clarke, Ambrose, Cummins, Eoin P., Cagney, Gerard, Taylor, Cormac T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039330/
https://ncbi.nlm.nih.gov/pubmed/21123177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115931
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