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A Novel Immunoregulatory Function for IL-23: Inhibition of IL-12 Dependent IFN-γ Production
Most studies investigating the function of IL-23 have concluded that it promotes IL-17 secreting T cells. While some reports have also characterized IL-23 as having redundant pro-inflammatory effects with IL-12, we have instead found that IL-23 antagonizes IL-12 induced secretion of IFN-γ. When sple...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039303/ https://ncbi.nlm.nih.gov/pubmed/20458705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939759 |
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