Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension

In the present study, we examined the effects of soluble epoxide hydrolase (sEH) inhibition on the development of angiotensin II-dependent hypertension and on renal function in transgenic rats with inducible expression of the mouse renin gene (strain name Cyp1a1-Ren-2). Hypertension was induced in t...

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Detalhes bibliográficos
Main Authors: Honetschlägerová, Zuzana, Husková, Zuzana, Vaňourková, Zdeňka, Sporková, Alexandra, Kramer, Herbert J, Hwang, Sung Hee, Tsai, Hsing-Ju, Hammock, Bruce D, Imig, John D, Červenka, Luděk, Kopkan, Libor
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Renal and Endocrine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039270/
https://ncbi.nlm.nih.gov/pubmed/21078594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.199505
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